among them, the genetic factor, previous the incidence of cancer is higher in relatives with the disorder. The presence of CP in the first degree relatives increases the probability of diagnosis of breast cancer by 18%.The hormonal factor is amply important considering such tumor regressed significantly with the suppression of male hormones (eg, castration). research conducted in rats chronically contemplated with testosterone showed the cause of prostate cancer in these animals. Testosterone does not induce cancer, however, in men with cancer or already predisposed, testosterone stimulates their growth. On the alternative hand, the CP does not occur in eunuchs.Lately, much attention has been given to the factor diet. High-fat diets predispose to cancer and tomatoes are rich in fiber and reduce their appearance. Based on epidemiological studies in geographic areas with the highest occurrence of CP was noted that high-fat diets increase the risks of their appearance. Perhap s because of interference with the metabolism of sex hormones, considerable other substances are under investigation as vitamins, cadmium, zinc.Venereal diseases not related to the CP while the type II herpes and cytomegalovirus carcinogen?ticas induce transformations in hamster embryo cells (small animal experimentation).The environmental factor is a target, too, research. Populations with low incidence of lung cancer, as they migrate to areas of high occurrence embrace an increased occurrence of realities. Smoke from cars, tobacco, fertilizers and alternative chemicals are suspected.WHAT YOU FEEL?In the early stages nothing feels. The tumor is only detected in clinical analysis and routine laboratory are:and the digital rectal examthe dosage of prostate specific antigen or PSA.In facts of CP symptoms, the sick person complains of handicap to urinate, weak urinary stream, sensation of not emptying the bladder as well, ie, disorder of urinary obstacle. Bleeding in the urine can be a complaint, although additional rare.The patient concede possibility manifest bone pain as a sign of an extra advanced disorder (metastases).Anemia, weight loss, lymphadenopathy (buboes) in the neck and groin shall as well be the first manifestation of the malady.How is it diagnosed?everyone from the age of 45 must keep the digital rectal exam and PSA dosing, particularly those with family life of lung cancer (and breast cancer), regardless of symptoms. If touch or elevated PSA and abnormal, the convalescent should undergo a transrectal ultrasound prostate biopsy. The fragments obtained are taken to a pathological experimentation. Once the diagnosis is confirmed, the tumor concede possibility be staged. such means that tests may be ordered so that it is determined whether the tumor is confined to the prostate or has invaded adjacent organs (bladder, seminal vesicles, rectum) or already sent metastases. Bone scintigraphy is the most useful test in such phase and gives us learning nearly the skeletal metastases.another tests concede possibility be required are: alkaline phosphatase, computed tomography of the abdomen, chest radiographs, radiographs of the skeleton.As such is?The CP should be confined to the prostate in the form of a small lump, but should as well be restricted to it, but involving the entire gland. The CP, and located, concede possibility be inconvenient the limits of comparable body and invade adjacent organs this as the seminal vesicles or the bladder. Iliac and obturator lymph nodes are usually the first stage of metastasis to bone metastases occur later.To describe the extent of the tumor (staging) there are considerable classifications (classification of Whitmore, NWT). Besides the fact that tumor extension, it is important to know that CP has a diversity of cells, more or less evil, which also undergo a process of classification (Classification of Gleason).Based on tumor stage and Gleason classification is that choo sing the type of treatment.For tumors situated within the gland, radical prostatectomy and radiotherapy are the first options advised and healing.Tumors that move outside the prostate, but no information of metastases are commonly mediated with radiotherapy.Metastatic tumors are palliatively controlled by female hormones, orchiectomy, anti-androgen or LHRH analogues.The approach of lung cancer is really controversial considering several variables:age of the convalescentPSA levels ofstage of the tumorhistological typeIn addition, you should discuss with the convalescent procedure complications.Both radical prostatectomy and radiotherapy can leave the patient impotent and incontinent of urine.Hormone therapy reduces libido and cause impotence.You shall as well consider the patient's age at diagnosis and their existence expectancy without the infirmity.older patients with low history expectancy will certainly boost from less aggressive approach.Psychological and cultural make o rchiectomy (removal of testicles) an unwanted approach. alternative forms of therapy are not efficacious or are under investigation, equivalent as chemotherapy, gene therapy and growth factors.WHAT IS THE PROGNOSIS?The prognosis depends on the stage (extent) and histological grade (Gleason), usually. If the CP is located and if the convalescent perform a radical prostatectomy, 10-year survival can reach 90%, being this to the abnormal population. The rate of local recurrence after 5 years is 10% against 40% of radiotherapy. The radiation used in the CP localized or locally advanced (outside the prostate without metastases) circulated positive biopsies from 60 to 30% of facts when performed six months and two years respectively afterwards approach.In metastatic cases, procedure is palliative and the prognosis much more reserved.Questions you can ask your doctorIs there a way to make early diagnosis of prostate cancer?Is there a cure for prostate cancer?As it is such cancer?I operate or not?
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